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Prolonged mitosis of neural progenitors alters cell fate in the developing brain

Embryonic neocortical development depends upon balanced production of progenitors and neurons. Genetic mutations disrupting progenitor mitosis frequently impair neurogenesis, however the link between altered mitosis and cell fate remains poorly understood. Here we demonstrate that prolonged mitosis...

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Detalhes bibliográficos
Publicado no:Neuron
Main Authors: Pilaz, Louis-Jan, McMahon, John J., Miller, Emily E., Lennox, Ashley L., Suzuki, Aussie, Salmon, Edward, Silver, Debra L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4706996/
https://ncbi.nlm.nih.gov/pubmed/26748089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2015.12.007
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