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A Cytoplasmic Heme Sensor Illuminates the Impacts of Mitochondrial and Vacuolar Functions and Oxidative Stress on Heme-Iron Homeostasis in Cryptococcus neoformans

Pathogens must compete with hosts to acquire sufficient iron for proliferation during pathogenesis. The pathogenic fungus Cryptococcus neoformans is capable of acquiring iron from heme, the most abundant source in vertebrate hosts, although the mechanisms of heme sensing and acquisition are not enti...

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Detalhes bibliográficos
Publicado no:mBio
Main Authors: Bairwa, Gaurav, Sánchez-León, Eddy, Do, Eunsoo, Jung, Won Hee, Kronstad, James W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7387795/
https://ncbi.nlm.nih.gov/pubmed/32723917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00986-20
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