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Genome-wide association study and polygenic risk score analysis of esketamine treatment response
To elucidate the genetic underpinnings of the antidepressant efficacy of S-ketamine (esketamine) nasal spray in major depressive disorder (MDD), we performed a genome-wide association study (GWAS) in cohorts of European ancestry (n = 527). This analysis was followed by a polygenic risk score approac...
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| Publicat a: | Sci Rep |
|---|---|
| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group UK
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7387452/ https://ncbi.nlm.nih.gov/pubmed/32724131 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-69291-6 |
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