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Extending the spacing between the Shine-Dalgarno sequence and P-site codon reduces the rate of mRNA translocation
By forming basepairing interactions with the 3’ end of 16S rRNA, mRNA Shine-Dalgarno (SD) sequences positioned upstream of Open Reading Frames (ORFs) facilitate translation initiation. During the elongation phase of protein synthesis, intragenic SD-like sequences stimulate ribosome frameshifting and...
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| Publicado no: | J Mol Biol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7387212/ https://ncbi.nlm.nih.gov/pubmed/32544497 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2020.06.008 |
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