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Role of HMGB1 signaling in the inflammatory process in diabetic retinopathy

High mobility group box 1 (HMGB1) is a key player in retinal inflammation. HMGB1 is a danger associated protein pattern receptor which can sense high glucose as a stressor. Increased HMGB1 levels have been found in patients with late stage diabetic retinopathy. HMGB1 can bind toll-like receptor 4 (T...

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Bibliografiske detaljer
Udgivet i:Cell Signal
Hovedforfatter: Steinle, Jena J.
Format: Artigo
Sprog:Inglês
Udgivet: 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7387203/
https://ncbi.nlm.nih.gov/pubmed/32497617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2020.109687
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