ABL1, Overexpressed in Hepatocellular Carcinomas, Regulates Expression of NOTCH1 and Promotes Development of Liver Tumors in Mice

BACKGROUND & AIMS: We investigated whether ABL proto-oncogene 1, non-receptor tyrosine kinase (ABL1) is involved in development of hepatocellular carcinoma (HCC). METHODS: We analyzed clinical and gene expression data from The Cancer Genome Atlas. Albumin-Cre (Hep(WT)) mice and mice with hepatoc...

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Detalhes bibliográficos
Publicado no:Gastroenterology
Main Authors: Wang, Fang, Hou, Wei, Chitsike, Lennox, Xu, Yingchen, Bettler, Carlee, Perera, Aldeb, Bank, Thomas, Cotler, Scott J., Dhanarajan, Asha, Denning, Mitchell F., Ding, Xianzhong, Breslin, Peter, Qiang, Wenan, Li, Jun, Koleske, Anthony J., Qiu, Wei
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7387191/
https://ncbi.nlm.nih.gov/pubmed/32171747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2020.03.013
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