Efficacy of single-agent immunosuppressive regimens in a murine model of vascularized composite allotransplantation

We herein investigate the safety and efficacy of single-agent anti-rejection regimens in a mouse vascularized composite allotransplantation (VCA) model. Orthotopic hind-limb transplantations (Balb/c → C57BL/6) were performed using 6- to 8-week-old mice. A thirty-day regimen of either rapamycin, tacr...

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Veröffentlicht in:Transpl Int
Hauptverfasser: Guo, Yinan, Messner, Franka, Etra, Joanna W., Beck, Sarah E., Kalsi, Richa, Furtmüller, Georg J., Schneeberger, Stefan, Oh, Byoung Chol, Brandacher, Gerald
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7387151/
https://ncbi.nlm.nih.gov/pubmed/32299127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/tri.13618
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