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Targeting Metabolism as a Platform for Inducing Allograft Tolerance in the Absence of Long-Term Immunosuppression

Transplant tolerance in the absence of long-term immunosuppression has been an elusive goal for solid organ transplantation. Recently, it has become clear that metabolic reprogramming plays a critical role in promoting T cell activation, differentiation, and function. Targeting metabolism can prefer...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Cheng, Chih-Hsien, Lee, Chen-Fang, Oh, Byoung Chol, Furtmüller, Georg J., Patel, Chirag H., Brandacher, Gerald, Powell, Jonathan D.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7161684/
https://ncbi.nlm.nih.gov/pubmed/32328063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.00572
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