Preventing allograft rejection by targeting immune metabolism

Upon antigen recognition and co-stimulation, T lymphocytes up-regulate the metabolic machinery necessary to proliferate and sustain effector function. This metabolic reprogramming in T cells regulates T cell activation and differentiation but is not just a consequence of antigen recognition. While s...

Full description

Saved in:
Bibliographic Details
Published in:Cell Rep
Main Authors: Lee, Chen-Fang, Lo, Ying-Chun, Cheng, Chih-Hsien, Furtmüller, Georg J., Oh, Byoungchol, Andrade-Oliveira, Vinicius, Thomas, Ajit G., Bowman, Caitlyn E., Slusher, Barbara S., Wolfgang, Michael J., Brandacher, Gerald, Powell, Jonathan D.
Format: Artigo
Language:Inglês
Published: 2015
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4626381/
https://ncbi.nlm.nih.gov/pubmed/26489460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.09.036
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items