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Human cohesin compacts DNA by loop extrusion

Cohesin is a chromosome-bound multisubunit ATPase complex. Following its loading onto chromosomes, cohesin generates chromosome loops to regulate chromosome functions. It has been suggested that cohesin organizes the genome via loop extrusion, but direct evidence is lacking. Here, we use single-mole...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Science
Egile Nagusiak: Kim, Yoori, Shi, Zhubing, Zhang, Hongshan, Finkelstein, Ilya J., Yu, Hongtao
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2019
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7387118/
https://ncbi.nlm.nih.gov/pubmed/31780627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aaz4475
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