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Human cohesin compacts DNA by loop extrusion
Cohesin is a chromosome-bound multisubunit ATPase complex. Following its loading onto chromosomes, cohesin generates chromosome loops to regulate chromosome functions. It has been suggested that cohesin organizes the genome via loop extrusion, but direct evidence is lacking. Here, we use single-mole...
Guardat en:
| Publicat a: | Science |
|---|---|
| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7387118/ https://ncbi.nlm.nih.gov/pubmed/31780627 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aaz4475 |
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