Interferons and viruses induce a novel primate-specific isoform dACE2 and not the SARS-CoV-2 receptor ACE2

Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), which causes COVID-19, utilizes angiotensin-converting enzyme 2 (ACE2) for entry into target cells. ACE2 has been proposed as an interferon-stimulated gene (ISG). Thus, interferon-induced variability in ACE2 expression levels could be imp...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:bioRxiv
Hlavní autoři: Onabajo, Olusegun O., Banday, A. Rouf, Yan, Wusheng, Obajemu, Adeola, Stanifer, Megan L., Santer, Deanna M., Florez-Vargas, Oscar, Piontkivska, Helen, Vargas, Joselin, Kee, Carmon, Tyrrell, D. Lorne J., Mendoza, Juan L., Boulant, Steeve, Prokunina-Olsson, Ludmila
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory 2020
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7386494/
https://ncbi.nlm.nih.gov/pubmed/32743577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2020.07.19.210955
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky