Dosage suppression genetic interaction networks enhance functional wiring diagrams of the cell

Dosage suppression is a genetic interaction in which overproduction of one gene rescues a mutant phenotype of another gene. Although dosage suppression is known to map functional connections among genes, the extent to which It might illuminate global cellular functions is unclear. Here we analyze a...

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Detalhes bibliográficos
Publicado no:Nat Biotechnol
Main Authors: Magtanong, Leslie, Ho, Cheuk Hei, Barker, Sarah L, Jiao, Wei, Baryshnikova, Anastasia, Bahr, Sondra, Smith, Andrew M, Heisler, Lawrence E, Choy, John S, Kuzmin, Elena, Andrusiak, Kerry, Kobylianski, Anna, Li, Zhijian, Costanzo, Michael, Basrai, Munira A, Giaever, Guri, Nislow, Corey, Andrewa, Brenda, Boone, Charles
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7386433/
https://ncbi.nlm.nih.gov/pubmed/21572441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt.1855
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