Identification of injury and shock driven effects on ex vivo platelet aggregometry: A cautionary tale of phenotyping

BACKGROUND: Platelet behavior in trauma-induced coagulopathy is poorly understood. Injured patients have impaired platelet aggregation (dysfunction) in ex vivo agonist-stimulated platelet aggregometry (PA). However, PA assumes that platelets are inactivated before ex vivo stimulated aggregation, whi...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Trauma Acute Care Surg
Egile Nagusiak: Starr, Nichole E., Matthay, Zachary A., Fields, Alexander T., Nunez-Garcia, Brenda, Callcut, Rachael A., Cohen, Mitchell J., Kornblith, Lucy Zumwinkle
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2020
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7386285/
https://ncbi.nlm.nih.gov/pubmed/32218020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/TA.0000000000002707
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