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Site-specific Bioconjugation and Convergent Click Chemistry Enhances Antibody–Chromophore Conjugate Binding Efficiency(†)

Photosensitizer (PS)–antibody conjugates (photoimmunoconjugates, PICs) enable cancer-cell targeted photodynamic therapy (PDT). Non-specific chemical bioconjugation is widely used to synthesize PICs but gives rise to several shortcomings. The conjugates are heterogenous, and the process is not easily...

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Foilsithe in:Photochem Photobiol
Main Authors: Sadiki, Amissi, Kercher, Eric M., Lu, Haibin, Lang, Ryan T., Spring, Bryan Q., Zhou, Zhaohui Sunny
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2020
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7386253/
https://ncbi.nlm.nih.gov/pubmed/32080860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/php.13231
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