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Novel Noncompetitive Type Three Secretion System ATPase Inhibitors Shut Down Shigella Effector Secretion

Shigella is the causative agent of bacillary dysentery and is responsible for an estimated 165 million infections and 600,000 deaths annually. Like many Gram-negative pathogens, Shigella relies on a type three secretion system (T3SS) to initiate and sustain infection by directly injecting effector p...

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Publicado en:Biochemistry
Autores principales: Case, Heather B., Mattock, Dominic S., Miller, Bill R., Dickenson, Nicholas E.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2020
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7386064/
https://ncbi.nlm.nih.gov/pubmed/32567308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.0c00431
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