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Shutting Down Shigella Secretion: Characterizing Small Molecule Type Three Secretion System ATPase Inhibitors

Many important human pathogens rely on one or more type three secretion systems (T3SS) to inject bacterial effector proteins directly into the host cell cytoplasm. Protein secretion through the needle-like type three secretion apparatus (T3SA) is essential for pathogen virulence and relies on a high...

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Detalhes bibliográficos
Publicado no:Biochemistry
Main Authors: Case, Heather B., Mattock, Dominic S., Dickenson, Nicholas E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6298828/
https://ncbi.nlm.nih.gov/pubmed/30460850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.8b01077
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