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EZH2: a novel target for cancer treatment
Enhancer of zeste homolog 2 (EZH2) is enzymatic catalytic subunit of polycomb repressive complex 2 (PRC2) that can alter downstream target genes expression by trimethylation of Lys-27 in histone 3 (H3K27me3). EZH2 could also regulate gene expression in ways besides H3K27me3. Functions of EZH2 in cel...
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| Publicado no: | J Hematol Oncol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7385862/ https://ncbi.nlm.nih.gov/pubmed/32723346 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13045-020-00937-8 |
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