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EZH2: novel therapeutic target for human cancer
Enhancer of Zeste homlog 2 (EZH2) is a catalytic subunit of epigenetic regulator Polycomb repressive complex 2 (PRC2), which trimethylates Lys 27 of histone H3, leading to silencing of the target genes that are involved in a variety of biological processes including tumor progression and stem cell m...
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| Publicado no: | Biomedicine (Taipei) |
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| Autor principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
China Medical University
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4264983/ https://ncbi.nlm.nih.gov/pubmed/25520914 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7603/s40681-014-0001-6 |
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