Activated invariant natural killer T cells directly recognize leukemia cells in a CD1d‐independent manner

Invariant natural killer T (iNKT) cells are innate‐like CD1d‐restricted T cells that express the invariant T cell receptor (TCR) composed of Vα24 and Vβ11 in humans. iNKT cells specifically recognize glycolipid antigens such as α‐galactosylceramide (αGalCer) presented by CD1d. iNKT cells show direct...

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Veröffentlicht in:Cancer Sci
Hauptverfasser: Aoki, Takahiro, Takami, Mariko, Takatani, Tomozumi, Motoyoshi, Kiwamu, Ishii, Ayana, Hara, Ayaka, Toyoda, Takahide, Okada, Reona, Hino, Moeko, Koyama‐Nasu, Ryo, Kiuchi, Masahiro, Hirahara, Kiyoshi, Kimura, Motoko Y., Nakayama, Toshinori, Shimojo, Naoki, Motohashi, Shinichiro
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2020
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Original Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7385353/
https://ncbi.nlm.nih.gov/pubmed/32324315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.14428
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