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Ribosome collisions trigger general stress responses to regulate cell fate

Problems arising during translation of mRNAs lead to ribosome stalling and collisions that trigger a series of quality control events. However, the global cellular response to ribosome collisions has not been explored. Here, we uncover a function for ribosome collisions in signal transduction. Using...

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Vydáno v:Cell
Hlavní autoři: Wu, Colin Chih-Chien, Peterson, Amy, Zinshteyn, Boris, Regot, Sergi, Green, Rachel
Médium: Artigo
Jazyk:Inglês
Vydáno: 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7384957/
https://ncbi.nlm.nih.gov/pubmed/32610081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2020.06.006
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