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Maternal Pregravid Obesity Remodels the DNA Methylation Landscape of Cord Blood Monocytes Disrupting its Inflammatory Program

Pre-pregnancy maternal obesity is associated with adverse outcomes for the offspring, including increased incidence of neonatal bacterial sepsis and necrotizing enterocolitis. We recently reported that umbilical cord blood (UCB) monocytes from babies born to obese mothers generate a reduced IL6/TNFα...

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Detalles Bibliográficos
Publicado en:J Immunol
Main Authors: Sureshchandra, Suhas, Wilson, Randall M., Rais, Maham, Marshall, Nicole E., Purnell, Jonathan Q., Thornburg, Kent L., Messaoudi, Ilhem
Formato: Artigo
Idioma:Inglês
Publicado: 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7384891/
https://ncbi.nlm.nih.gov/pubmed/28887432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1700434
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