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IDG-SW3 Osteocyte Differentiation and Bone Extracellular Matrix Deposition Are Enhanced in a 3D Matrix Metalloproteinase-Sensitive Hydrogel

Osteocytes reside within a heavily mineralized matrix making them difficult to study in vivo and to extract for studies in vitro. IDG-SW3 cells are capable of producing mineralized collagen matrix and transitioning from osteoblasts to mature osteocytes, thus offering an alternative to study osteobla...

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Foilsithe in:ACS Appl Bio Mater
Main Authors: Aziz, Aaron H., Wilmoth, Rachel L., Ferguson, Virginia L., Bryant, Stephanie J.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2020
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7384758/
https://ncbi.nlm.nih.gov/pubmed/32719827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsabm.9b01227
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