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A 3D, Dynamically Loaded Hydrogel Model of the Osteochondral Unit to Study Osteocyte Mechanobiology

Osteocytes are mechanosensitive cells that orchestrate signaling in bone and cartilage across the osteochondral unit. The mechanisms by which osteocytes regulate osteochondral homeostasis and degeneration in response to mechanical cues remain unclear. This study introduces a novel 3D hydrogel bilaye...

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Detalhes bibliográficos
Publicado no:Adv Healthc Mater
Main Authors: Wilmoth, Rachel L., Ferguson, Virginia L., Bryant, Stephanie J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7677224/
https://ncbi.nlm.nih.gov/pubmed/33073541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/adhm.202001226
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