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A 3D, Dynamically Loaded Hydrogel Model of the Osteochondral Unit to Study Osteocyte Mechanobiology

Osteocytes are mechanosensitive cells that orchestrate signaling in bone and cartilage across the osteochondral unit. The mechanisms by which osteocytes regulate osteochondral homeostasis and degeneration in response to mechanical cues remain unclear. This study introduces a novel 3D hydrogel bilaye...

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Detalles Bibliográficos
Publicado en:Adv Healthc Mater
Main Authors: Wilmoth, Rachel L., Ferguson, Virginia L., Bryant, Stephanie J.
Formato: Artigo
Idioma:Inglês
Publicado: 2020
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7677224/
https://ncbi.nlm.nih.gov/pubmed/33073541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/adhm.202001226
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