The Aspergillus fumigatus transcription factor RglT is important for gliotoxin biosynthesis and self-protection, and virulence

Aspergillus fumigatus is an opportunistic fungal pathogen that secretes an array of immune-modulatory molecules, including secondary metabolites (SMs), which contribute to enhancing fungal fitness and growth within the mammalian host. Gliotoxin (GT) is a SM that interferes with the function and recr...

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Bibliografische gegevens
Gepubliceerd in:PLoS Pathog
Hoofdauteurs: Ries, Laure N. A., Pardeshi, Lakhansing, Dong, Zhiqiang, Tan, Kaeling, Steenwyk, Jacob L., Colabardini, Ana Cristina, Ferreira Filho, Jaire A., de Castro, Patricia A., Silva, Lilian P., Preite, Nycolas W., Almeida, Fausto, de Assis, Leandro J., dos Santos, Renato A. C., Bowyer, Paul, Bromley, Michael, Owens, Rebecca A., Doyle, Sean, Demasi, Marilene, Hernández, Diego C. R., Netto, Luís Eduardo S., Pupo, Monica T., Rokas, Antonis, Loures, Flavio V., Wong, Koon H., Goldman, Gustavo H.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2020
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7384679/
https://ncbi.nlm.nih.gov/pubmed/32667960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1008645
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