Gliotoxin, a Known Virulence Factor in the Major Human Pathogen Aspergillus fumigatus, Is Also Biosynthesized by Its Nonpathogenic Relative Aspergillus fischeri

Aspergillus fumigatus is a major opportunistic human pathogen. Multiple traits contribute to A. fumigatus pathogenicity, including its ability to produce specific secondary metabolites, such as gliotoxin. Gliotoxin is known to inhibit the host immune response, and genetic mutants that inactivate gli...

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Vydáno v:mBio
Hlavní autoři: Knowles, Sonja L., Mead, Matthew E., Silva, Lilian Pereira, Raja, Huzefa A., Steenwyk, Jacob L., Goldman, Gustavo H., Oberlies, Nicholas H., Rokas, Antonis
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2020
Témata:
Observation
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7018655/
https://ncbi.nlm.nih.gov/pubmed/32047138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.03361-19
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