Gliotoxin, a Known Virulence Factor in the Major Human Pathogen Aspergillus fumigatus, Is Also Biosynthesized by Its Nonpathogenic Relative Aspergillus fischeri

Aspergillus fumigatus is a major opportunistic human pathogen. Multiple traits contribute to A. fumigatus pathogenicity, including its ability to produce specific secondary metabolites, such as gliotoxin. Gliotoxin is known to inhibit the host immune response, and genetic mutants that inactivate gli...

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Detalhes bibliográficos
Publicado no:mBio
Main Authors: Knowles, Sonja L., Mead, Matthew E., Silva, Lilian Pereira, Raja, Huzefa A., Steenwyk, Jacob L., Goldman, Gustavo H., Oberlies, Nicholas H., Rokas, Antonis
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2020
Assuntos:
Observation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7018655/
https://ncbi.nlm.nih.gov/pubmed/32047138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.03361-19
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