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Fecal microbiota transplantation from metabolically compromised human donors accelerates osteoarthritis in mice
OBJECTIVES: Emerging evidence suggests the microbiome plays an important role in the pathogenesis of osteoarthritis (OA). We aimed to test the two-hit model of OA pathogenesis and potentiation in which one ‘hit’ is provided by an adverse gut microbiome that activates innate immunity; the other ‘hit’...
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| 出版年: | Ann Rheum Dis |
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| 主要な著者: | , , , , , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2020
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7384301/ https://ncbi.nlm.nih.gov/pubmed/32205337 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/annrheumdis-2019-216471 |
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