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Technical Note: The development of a multi‐physics simulation tool to estimate the background dose by systemic targeted alpha therapy

PURPOSE: To predict biological effects of targeted alpha therapy (TAT) in preclinical studies, dosimetry calculations based on the micro‐level distributions of emitters are essential. Due to the saturation of the tumor antigenic sites and bonding breaks by decay, some of Alpha‐immuno‐conjugate and d...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Med Phys
Hauptverfasser: Xu, T., Liu, T., Li, G., Dugal, C., Aydemir, N. A., Liu, Y., Roeske, J. C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7384137/
https://ncbi.nlm.nih.gov/pubmed/32129888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mp.14111
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