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Technical Note: The development of a multi‐physics simulation tool to estimate the background dose by systemic targeted alpha therapy

PURPOSE: To predict biological effects of targeted alpha therapy (TAT) in preclinical studies, dosimetry calculations based on the micro‐level distributions of emitters are essential. Due to the saturation of the tumor antigenic sites and bonding breaks by decay, some of Alpha‐immuno‐conjugate and d...

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Dettagli Bibliografici
Pubblicato in:Med Phys
Autori principali: Xu, T., Liu, T., Li, G., Dugal, C., Aydemir, N. A., Liu, Y., Roeske, J. C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2020
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7384137/
https://ncbi.nlm.nih.gov/pubmed/32129888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mp.14111
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