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Comparison of In Vitro and In Vivo Percutaneous Absorption Across Human Skin Using BAY1003803 Formulated as Ointment and Cream

Direct comparisons between skin absorption data and clinical pharmacokinetic data are rare. Here we use the lipophilic nonsteroidal selective glucocorticoid receptor agonist BAY1003803 to make such a comparison. The objective is to find the extent to which measurements of skin permeation in vitro ca...

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Podrobná bibliografie
Vydáno v:Clin Pharmacol Drug Dev
Hlavní autoři: Günther, Clemens, Kowal, Kristin, Schmidt, Timm, Jambrecina, Alen, Toner, Frank, Nave, Rüdiger
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7383986/
https://ncbi.nlm.nih.gov/pubmed/31647607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cpdd.736
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