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Comparison of In Vitro and In Vivo Percutaneous Absorption Across Human Skin Using BAY1003803 Formulated as Ointment and Cream

Direct comparisons between skin absorption data and clinical pharmacokinetic data are rare. Here we use the lipophilic nonsteroidal selective glucocorticoid receptor agonist BAY1003803 to make such a comparison. The objective is to find the extent to which measurements of skin permeation in vitro ca...

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書目詳細資料
發表在:Clin Pharmacol Drug Dev
Main Authors: Günther, Clemens, Kowal, Kristin, Schmidt, Timm, Jambrecina, Alen, Toner, Frank, Nave, Rüdiger
格式: Artigo
語言:Inglês
出版: John Wiley and Sons Inc. 2019
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7383986/
https://ncbi.nlm.nih.gov/pubmed/31647607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cpdd.736
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