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A General Regioselective Synthesis of Alcohols by Cobalt‐Catalyzed Hydrogenation of Epoxides

A straightforward methodology for the synthesis of anti‐Markovnikov‐type alcohols is presented. By using a specific cobalt triphos complex in the presence of Zn(OTf)(2) as an additive, the hydrogenation of epoxides proceeds with high yields and selectivities. The described protocol shows a broad sub...

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Detalhes bibliográficos
Publicado no:Angew Chem Int Ed Engl
Main Authors: Liu, Weiping, Leischner, Thomas, Li, Wu, Junge, Kathrin, Beller, Matthias
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7383699/
https://ncbi.nlm.nih.gov/pubmed/32196878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.202002844
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