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Extra-telomeric impact of telomeres: Emerging molecular connections in pluripotency or stemness

Telomeres comprise specialized nucleic acid–protein complexes that help protect chromosome ends from DNA damage. Moreover, telomeres associate with subtelomeric regions through looping. This results in altered expression of subtelomeric genes. Recent observations further reveal telomere length–depen...

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Pubblicato in:J Biol Chem
Autori principali: Vinayagamurthy, Soujanya, Ganguly, Akansha, Chowdhury, Shantanu
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7383370/
https://ncbi.nlm.nih.gov/pubmed/32444498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.REV119.009710
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