Molecular insights into the heterogeneity of telomere reprogramming in induced pluripotent stem cells

Rejuvenation of telomeres with various lengths has been found in induced pluripotent stem cells (iPSCs). Mechanisms of telomere length regulation during induction and proliferation of iPSCs remain elusive. We show that telomere dynamics are variable in mouse iPSCs during reprogramming and passage, a...

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Hlavní autoři: Wang, Fang, Yin, Yu, Ye, Xiaoying, Liu, Kai, Zhu, Haiying, Wang, Lingling, Chiourea, Maria, Okuka, Maja, Ji, Guangzhen, Dan, Jiameng, Zuo, Bingfeng, Li, Minshu, Zhang, Qian, Liu, Na, Chen, Lingyi, Pan, Xinghua, Gagos, Sarantis, Keefe, David L, Liu, Lin
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2012
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3317559/
https://ncbi.nlm.nih.gov/pubmed/22184006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2011.201
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