The Evolutionarily Conserved piRNA-producing Locus pi6 Is Required for Male Mouse Fertility

Pachytene piRNAs, which comprise >80% of small RNAs in the adult mouse testis, have been proposed to bind and regulate target RNAs like miRNAs, cleave targets like siRNAs, or lack biological function altogether. Although piRNA pathway protein mutants are male sterile, no biological function has b...

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Gepubliceerd in:Nat Genet
Hoofdauteurs: Wu, Pei-Hsuan, Fu, Yu, Cecchini, Katharine, Özata, Deniz M., Arif, Amena, Yu, Tianxiong, Colpan, Cansu, Gainetdinov, Ildar, Weng, Zhiping, Zamore, Phillip D.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2020
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7383350/
https://ncbi.nlm.nih.gov/pubmed/32601478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41588-020-0657-7
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