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Histone acetyltransferase inhibition rescues differentiation of emerin-deficient myogenic progenitors

INTRODUCTION: Emery-Dreifuss muscular dystrophy (EDMD) is a disease characterized by skeletal muscle wasting, major tendon contractures, and cardiac conduction defects. Mutations in the gene encoding emerin cause EDMD1. Our previous studies suggested that emerin activation of histone deacetylase 3 (...

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Bibliografische gegevens
Gepubliceerd in:Muscle Nerve
Hoofdauteurs: Bossone, Katherine A., Ellis, Joseph A., Holaska, James M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2020
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7382944/
https://ncbi.nlm.nih.gov/pubmed/32304242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mus.26892
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