Causal mutations from adaptive laboratory evolution are outlined by multiple scales of genome annotations and condition-specificity

BACKGROUND: Adaptive Laboratory Evolution (ALE) has emerged as an experimental approach to discover mutations that confer phenotypic functions of interest. However, the task of finding and understanding all beneficial mutations of an ALE experiment remains an open challenge for the field. To provide...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:BMC Genomics
Auteurs principaux: Phaneuf, Patrick V., Yurkovich, James T., Heckmann, David, Wu, Muyao, Sandberg, Troy E., King, Zachary A., Tan, Justin, Palsson, Bernhard O., Feist, Adam M.
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2020
Sujets:
Methodology Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7382830/
https://ncbi.nlm.nih.gov/pubmed/32711472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-020-06920-4
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires