Causal mutations from adaptive laboratory evolution are outlined by multiple scales of genome annotations and condition-specificity

BACKGROUND: Adaptive Laboratory Evolution (ALE) has emerged as an experimental approach to discover mutations that confer phenotypic functions of interest. However, the task of finding and understanding all beneficial mutations of an ALE experiment remains an open challenge for the field. To provide...

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Detalhes bibliográficos
Publicado no:BMC Genomics
Main Authors: Phaneuf, Patrick V., Yurkovich, James T., Heckmann, David, Wu, Muyao, Sandberg, Troy E., King, Zachary A., Tan, Justin, Palsson, Bernhard O., Feist, Adam M.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Methodology Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7382830/
https://ncbi.nlm.nih.gov/pubmed/32711472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-020-06920-4
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