Evidence for GTKO/β4GalNT2KO Pigs as the Preferred Organ-source for Old World Nonhuman Primates as a Preclinical Model of Xenotransplantation

BACKGROUND. Triple-knockout (TKO) pigs (in which expression of the 3 known pig carbohydrate xenoantigens has been deleted) are likely to be an optimal source of organs for transplantation into human recipients, many of whom do not have natural antibodies against TKO pig cells. However, old world mon...

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Detaylı Bibliyografya
Yayımlandı:Transplant Direct
Asıl Yazarlar: Cui, Yehua, Yamamoto, Takayuki, Raza, Syed Sikandar, Morsi, Mahmoud, Nguyen, Huy Quoc, Ayares, David, Cooper, David K.C., Hara, Hidetaka
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Lippincott Williams & Wilkins 2020
Konular:
Xenotransplantation
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7382549/
https://ncbi.nlm.nih.gov/pubmed/32766438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/TXD.0000000000001038
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