A novel therapeutic antibody screening method using bacterial high-content imaging reveals functional antibody binding phenotypes of Escherichia coli ST131

The increase of antimicrobial resistance (AMR), and lack of new classes of licensed antimicrobials, have made alternative treatment options for AMR pathogens increasingly attractive. Recent studies have demonstrated anti-bacterial efficacy of a humanised monoclonal antibody (mAb) targeting the O25b...

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Publicado no:Sci Rep
Main Authors: Maes, Mailis, Dyson, Zoe A., Smith, Sarah E., Goulding, David A., Ludden, Catherine, Baker, Stephen, Kellam, Paul, Reece, Stephen T., Dougan, Gordon, Bartholdson Scott, Josefin
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7382476/
https://ncbi.nlm.nih.gov/pubmed/32709982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-69300-8
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