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Computational approach towards identification of pathogenic missense mutations in AMELX gene and their possible association with amelogenesis imperfecta

Amelogenin gene (AMEL-X) encodes an enamel protein called amelogenin, which plays a vital role in tooth development. Any mutations in this gene or the associated pathway lead to developmental abnormalities of the tooth. The present study aims to analyze functional missense mutations in AMEL-X genes...

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Bibliografiske detaljer
Udgivet i:Mol Biol Res Commun
Main Authors: Shivani, Narendra, Smiline-Girija, Aseervatham Selvi, Paramasivam, Arumugam, Vijayashree-Priyadharsini, Jayaseelan
Format: Artigo
Sprog:Inglês
Udgivet: Shiraz University 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7382399/
https://ncbi.nlm.nih.gov/pubmed/32802900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.22099/mbrc.2020.35413.1456
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