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Computational approach towards identification of pathogenic missense mutations in AMELX gene and their possible association with amelogenesis imperfecta

Amelogenin gene (AMEL-X) encodes an enamel protein called amelogenin, which plays a vital role in tooth development. Any mutations in this gene or the associated pathway lead to developmental abnormalities of the tooth. The present study aims to analyze functional missense mutations in AMEL-X genes...

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Detalhes bibliográficos
Publicado no:Mol Biol Res Commun
Main Authors: Shivani, Narendra, Smiline-Girija, Aseervatham Selvi, Paramasivam, Arumugam, Vijayashree-Priyadharsini, Jayaseelan
Formato: Artigo
Idioma:Inglês
Publicado em: Shiraz University 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7382399/
https://ncbi.nlm.nih.gov/pubmed/32802900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.22099/mbrc.2020.35413.1456
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