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Towards an improved early diagnosis of neurodegenerative diseases: the emerging role of in vitro conversion assays for protein amyloids

Tissue accumulation of abnormal aggregates of amyloidogenic proteins such as prion protein, α-synuclein, and tau represents the hallmark of most common neurodegenerative disorders and precedes the onset of symptoms by years. As a consequence, the sensitive and specific detection of abnormal forms of...

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Detalhes bibliográficos
Publicado no:Acta Neuropathol Commun
Main Authors: Candelise, Niccolò, Baiardi, Simone, Franceschini, Alessia, Rossi, Marcello, Parchi, Piero
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7382043/
https://ncbi.nlm.nih.gov/pubmed/32711575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-020-00990-x
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