Piperaquine resistant Cambodian Plasmodium falciparum clinical isolates: in vitro genotypic and phenotypic characterization

BACKGROUND: High rates of dihydroartemisinin–piperaquine (DHA–PPQ) treatment failures have been documented for uncomplicated Plasmodium falciparum in Cambodia. The genetic markers plasmepsin 2 (pfpm2), exonuclease (pfexo) and chloroquine resistance transporter (pfcrt) genes are associated with PPQ r...

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書誌詳細
出版年:Malar J
主要な著者: Boonyalai, Nonlawat, Vesely, Brian A., Thamnurak, Chatchadaporn, Praditpol, Chantida, Fagnark, Watcharintorn, Kirativanich, Kirakarn, Saingam, Piyaporn, Chaisatit, Chaiyaporn, Lertsethtakarn, Paphavee, Gosi, Panita, Kuntawunginn, Worachet, Vanachayangkul, Pattaraporn, Spring, Michele D., Fukuda, Mark M., Lon, Chanthap, Smith, Philip L., Waters, Norman C., Saunders, David L., Wojnarski, Mariusz
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2020
主題:
Research
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7382038/
https://ncbi.nlm.nih.gov/pubmed/32711538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12936-020-03339-w
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