Neuroprotective Effect of Mesenchymal Stromal Cell-Derived Extracellular Vesicles Against Cerebral Ischemia-Reperfusion-Induced Neural Functional Injury: A Pivotal Role for AMPK and JAK2/STAT3/NF-κB Signaling Pathway Modulation

INTRODUCTION: Cerebral ischemia-reperfusion injury (CIRI) is the main factor that leads to poor prognosis of cerebral ischemia. Apoptosis has been shown to occur during the process of CIRI. Extracellular vesicles derived from mesenchymal stromal cells (MSCs-EVs) have shown broad potential for treati...

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Detalhes bibliográficos
Publicado no:Drug Des Devel Ther
Main Authors: Han, Min, Cao, Ying, Xue, Hao, Chu, Xili, Li, Tingting, Xin, Danqing, Yuan, Lin, Ke, Hongfei, Li, Gang, Wang, Zhen
Formato: Artigo
Idioma:Inglês
Publicado em: Dove 2020
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Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7381771/
https://ncbi.nlm.nih.gov/pubmed/32764885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S248892
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