Dexmedetomidine protects against renal ischemia and reperfusion injury by inhibiting the JAK/STAT signaling activation

BACKGROUND: The α(2)-adrenoreceptor agonist dexmedetomidine is known to provide renoprotection against ischemia and reperfusion (I/R) injury. However the underlying molecular mechanisms remain unclear. The purpose of this study was to investigate whether the Janus kinase and signal transducer and ac...

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Autori principali: Si, Yanna, Bao, Hongguang, Han, Liu, Shi, Hongwei, Zhang, Yuan, Xu, Li, Liu, Chenhui, Wang, Jinsong, Yang, Xiaobing, Vohra, Akbar, Ma, Daqing
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2013
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3700850/
https://ncbi.nlm.nih.gov/pubmed/23759023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-5876-11-141
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