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Cyclin D1 targets hexokinase 2 to control aerobic glycolysis in myeloma cells
Cancer cells are characterized by the Warburg effect, a shift from mitochondrial respiration to oxidative glycolysis. We report here the crucial role of cyclin D1 in promoting this effect in a cyclin-dependent kinase (CDK)4/6-independent manner in multiple myeloma (MM) cells. We show that the cyclin...
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| Izdano u: | Oncogenesis |
|---|---|
| Glavni autori: | , , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Nature Publishing Group UK
2020
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7381668/ https://ncbi.nlm.nih.gov/pubmed/32709889 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41389-020-00253-3 |
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