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Peripherally induced brain tissue-resident memory CD8(+) T cells mediate protection against CNS infection

The central nervous system (CNS) is classically viewed as immune-privileged; however, recent advances highlight interactions between the peripheral immune system and CNS in controlling infections and tissue homeostasis. Tissue-resident memory (Trm) CD8(+) T cells in the CNS are generated after brain...

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Vydáno v:Nat Immunol
Hlavní autoři: Urban, Stina L., Jensen, Isaac J., Shan, Qiang, Pewe, Lecia L., Xue, Hai-Hui, Badovinac, Vladimir P., Harty, John T.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7381383/
https://ncbi.nlm.nih.gov/pubmed/32572242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41590-020-0711-8
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