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3K3A-activated protein C variant does not interfere with the plasma clot lysis activity of tenecteplase
BACKGROUND AND PURPOSE —: A recombinant engineered variant of activated protein C (APC), 3K3A-APC, lacks anticoagulant properties (<10%) while preserving APC’s anti-inflammatory, anti-apoptotic, and neuroprotective functions and is very promising in clinical trials for ischemic stroke. Therapeuti...
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| Publicado no: | Stroke |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7380733/ https://ncbi.nlm.nih.gov/pubmed/32568648 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/STROKEAHA.120.028793 |
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