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Comparison of clot lysis activity and biochemical properties of originator tenecteplase (Metalyse(®)) with those of an alleged biosimilar

The bioengineered tissue plasminogen activator tenecteplase is an important treatment modality of acute myocardial infarction recommended by international guidelines. Following introduction of originator tenecteplase (brand names Metalyse(®) and TNKase(®)), a “biosimilar” tenecteplase became availab...

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Detalhes bibliográficos
Main Authors: Kliche, Werner, Krech, Ingo, Michel, Martin C., Sangole, Nishant V., Sathaye, Sadhana
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3914156/
https://ncbi.nlm.nih.gov/pubmed/24550831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2014.00007
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